SKU: 11266624835

Shedding, Haaren

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Description

Shedding, HaarenReduzierter Haarausfall (MC5R) ist ein komplexes genetisches Merkmal, das alle Rassen betreffen kann und epistatische Wechselwirkungen mit FGF5 (Felllnge) und RSPO2 (Fellbeschaffenheit) hat, die ebenfalls die Haarmorphologie bei Hunden beeinflussen. Diese Loci haben aufgrund einer starken knstlichen Selektion fr das Fellphnotyp selektive Sweeps durchlaufen. Die MC5R Proteinsequenz ist evolutionr bei Sugetieren konserviert, und eine bestimmte Mutation

Reduzierter Haarausfall (MC5R) ist ein komplexes genetisches Merkmal, das alle Rassen betreffen kann und epistatische Wechselwirkungen mit FGF5 (Felllänge) und RSPO2 (Fellbeschaffenheit) hat, die ebenfalls die Haarmorphologie bei Hunden beeinflussen. Diese Loci haben aufgrund einer starken künstlichen Selektion für das Fellphänotyp selektive Sweeps durchlaufen. Die MC5R-Proteinsequenz ist evolutionär bei Säugetieren konserviert, und eine bestimmte Mutation verursacht eine konformationale Änderung in der Tertiärstruktur des Proteins, das an der Produktion von Talg beteiligt ist, was die Wasserabweisung und Thermoregulation beeinflusst und zu erhöhtem Haarausfall führen kann. Der Gentest kann das Ausmaß des Haarausfalls bei einem Hund offenbaren, was helfen kann, geeignete Hunde für die Zucht auszuwählen und den Haarausfall zu reduzieren. Da einzelne Gene nur Durchschnittswerte für den Haarausfall liefern, ist es fast notwendig, die Kombination der Gene MC5R und RSPO2 zu testen.

Im Folgenden sind 3 Tabellen aufgeführt, die das Ausmaß des Haarausfalls je nach Genotyp zeigen; die letzte veranschaulicht das Ausmaß des Haarausfalls je nach Genotypkombination von MC5R und RSPO2.

MC5R

Genotyp

Grad des Haarausfalls

SD/SD

Niedrig

SD/N

Moderat

N/N

Hoch

N – Wildtyp-Allel, SD - Variantenallel

Hunde mit einem oder zwei Kopien der Variantenallele verlieren weniger Haare als Hunde ohne Kopien.

RSPO2

Genotyp

Grad des Haarausfalls

F/F

Niedrig

F/N

Moderat

N/N

Hoch

F/F - Fellbeschaffenheit, N/F - Fellbeschaffenheit, N/N - unzureichendes Fell

KOMBINATION VON MC5R UND RSPO2

Genotyp MC5R

Genotyp RSPO2

Grad des Haarausfalls

SD/SD

F/F

0

SD/SD

F/N

1

SD/SD

N/N

2

SD/N

F/F

1

SD/N

F/N

2

SD/N

N/N

3

N/N

F/F

2

N/N

F/N

3

N/N

N/N

4

Grade des Haarausfalls: niedrig 0 < 1 < 2 < 3 < 4 hoch

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SKU: 11266624835

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4.4 ★★★★★
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lovemykids
Phoenix, US
★★★★★ 5
Perfect to brighten up a room
Color: Beige Striped, Size: Queen
Nice comforter!
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Reviewed in the United States on May 13, 2026
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Verified Purchase
Avelino De Jesus
Port Orchard, US
★★★★★ 5
Very good feel soft and there right size
Color: Beige Striped, Size: Queen
They are very nice and soft the matching pillow cases are big so you can put fluffy pillows in it they seam to be durable and the size is perfect they feel really soft to sleep with and they will also keep you warm Over all I recommend these comforter sets
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Reviewed in the United States on December 16, 2025
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Theresa R.
Dallas, US
★★★★★ 1
Poor quality
Poor design, pre drilled holes did not align. Had to throw it away.
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Reviewed in the United States on September 16, 2025
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Verified Purchase
Seb
Whiting, US
★★★★★ 4
Good
Pretty easy to setup. The directions were easy to follow I setup in less than an hour. It’s kind of flimsy when moving it around but holds up well for sleep. Not squeaky at all.
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Reviewed in the United States on August 29, 2025
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Verified Purchase
Trevor T.
Waukegan, US
★★★★★ 3
Wooden slats not sturdy enough.
The bed frame looks nice, but the holes were not all aligned well, and with a bit of wrangling we were able to get it assembled with two people in about 45 minutes. The box was small, and the side rails are actually two pieces. Be careful because I pinched my hand pretty good when trying to align them after everything had been screwed together. The slats that go under the mattress are very thin and I'm concerned that they will break eventually. I think the company could have used better wood for the slats and still charged the same price. It's so hard to read through a ton of reviews to decide which bed frame to buy. This one is OK, but I see myself having to purchase wood in the future to replace the slats. It's long enough for a grown young man of 6'1" to sleep on it, but if my kids were younger and prone to jumping on beds, I'm sure it would break.
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Reviewed in the United States on October 26, 2025

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