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Description
Biotinylated LAIR2/CD306 His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms LAIR2, CD306 Accession Q6ISS4 Amino Acid Sequence Gln22 Pro152, with C terminal 8*His&Avi tag QEGALPRPSISAEPGTVISPGSHVTFMCRGPVGVQTFRLEREDRAKYKDSYNVFRLGPSESEARFHIDSVSEGNAGLYRCLYYKPPGWSEHSDFLELLVKESSGGPDSPDTEPGSSAGTVPGTEASGFDAPIEGRMDHHHHHHHHGLNDIFEAQKIEWHE Expression System HEK293 Molecular Weight 20 25kDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance
Product Specification
| Species | Human |
| Synonyms | LAIR2, CD306 |
| Accession | Q6ISS4 |
| Amino Acid Sequence | Gln22-Pro152, with C-terminal 8*His&Avi tag QEGALPRPSISAEPGTVISPGSHVTFMCRGPVGVQTFRLEREDRAKYKDSYNVFRLGPSESEARFHIDSVSEGNAGLYRCLYYKPPGWSEHSDFLELLVKESSGGPDSPDTEPGSSAGTVPGTEASGFDAPIEGRMDHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 20-25kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Lebbink R J. et al. (2008) The Soluble Leukocyte-Associated Ig-Like Receptor (LAIR)-2 Antagonizes the Collagen/LAIR-1 Inhibitory Immune Interaction. J Immunol. 180(3): 1662-1669. |
Background
The leukocyte-associated Ig-like receptor-2 (CD306) is an ITIM-containing inhibitory immune receptor, belonging to the Ig superfamily. LAIR-2 is encoded by a gene located in the vicinity of the LAIR-1 gene in the leukocyte receptor complex on human chromosome 19q13.4. The predicted LAIR-2 protein has a single Ig-like domain sharing 84% sequence homology with hLAIR-1, and the molecule lacks a transmembrane and cytoplasmic region suggesting it is a secreted protein. In contrast to hLAIR-1, LAIR-2 has no orthologs in mice or rats. The membrane ligand for LAIR-1 and LAIR-2 was expressed extensively and ligand recognition was of cross-species. LAIR-2 blocked the interaction of LAIR-1 with its ligand but LAIR-1 didn't block the interaction of LAIR-2 with its ligand. LAIR-2 had a higher affinity for collagen than did LAIR-1. LAIR-2 is a more potent antagonist of LAIR-1 function in vivo, while both sLAIR-1 and LAIR-2 are potential biomarkers. Recently shown that recombinant LAIR-2–His is able to interfere with collagen-induced platelet aggregation and that it efficiently inhibits the binding of collagen to glycoprotein VI and von Willebrand factor.
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4.2 ★★★★★
Based on 27 reviews
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Product Reviews
★★★★★ 5
Easy, great function paper towel holder!
Color: Silver
This paper towel holder is the best I’ve ever had. Extremely easy to
Put together - instructions are included but you really don’t need them - just screw the metal tube into the base. It’s heavy enough to hold the paper towels securely and ease to take individual sheets. I have one for quite some time now and just bought this one for my son and daughter-in-law. It comes well packaged and came quickly. Very stable, perfect size and easy to use!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 28, 2026
★★★★★ 5
Easy & Functional
Color: Silver
Thanks for the lovely note! This is a nice product. I will say the top ring is shiny chrome while the rest of the product is matte. I'm not overly picky so it's fine I'm my bathroom. Works great with no issues.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 30, 2026
★★★★★ 5
Great dish soap, cloth and scrubbies organizer!
Color: Black, Size: with Dishcloth Holder, Color: Black, Size: with Dishcloth Holder
I love the fact that it holds all my tools for the dishes. It helps to keep the area tidy.
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Reviewed in the United States on May 9, 2026
★★★★★ 5
Great organizational tool!
Color: Silver, Size: with Dishcloth Holder
Looks nice and keeps everything in it's place!
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Reviewed in the United States on May 7, 2026
★★★★★ 4
sturdy and they work well
Color: Black, Size: with Dishcloth Holder
my husband been complaining we need something in there to put sponges, etc. in and I’ve agreed with him for two or three years now we bought some different things and none of them really worked. They weren’t what I wanted.
I saw this and bought it and it’s definitely worth the money. It looks great. It’s easy to install sturdy. It’s going to drain easily and it has one of the top little baskets that you can move to wherever you want it I couldn’t ask for anything better this is going to be definitely what we wanted.
I just tried other things that go over the faucet and things like that and they did not look right and they were flimsy so before you buy one of those check this out first if you have enough room by
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Reviewed in the United States on November 22, 2025
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