SKU: 51744310902

YK-11 Poeder, 1gr

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Description

YK-11 Poeder, 1grYK 11 Wat is YK 11? YK 11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer. Onderzoek en eigenschappen Een studie van Lee et al. onderzocht YK 11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee

YK-11

Wat is YK-11?

YK-11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer.

Onderzoek en eigenschappen

Een studie van Lee et al. onderzocht YK-11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee verschillende doses YK-11 toegediend (oraal, 350 mg/kg en 700 mg/kg), waarna ze blootgesteld werden aan een peritoneale injectie van E. coli-bacteriën.

Het onderzoek toonde aan dat YK-11 de werking van myostatine remt — een hormoon dat spiergroei beperkt (bron). Behandelde muizen behielden hun lichaamsmassa tijdens ziekte en hadden een gunstigere vet-spierverhouding ten opzichte van de controlegroep.

Na blootstelling aan systemische E. coli konden de behandelde muizen spiermassa in rug en dijen beter herstellen. Hun spiercellen waren bovendien beter bestand tegen atrofie.

Effecten op immuunrespons en organen

Naast effecten op spiermassa, had YK-11 ook impact op de immuunreactie. Behandeling resulteerde in een verlaging van endotoxines en ontstekingsmarkers in de longen. Ook biomarkers voor orgaanschade — zoals AST, ALT en BUN — waren verlaagd.

De eliminatie van schadelijke bacteriën uit organen werd verbeterd bij muizen die met YK-11 waren behandeld (bron), en het overlevingspercentage na sepsis bleek hoger tot aan het 72-uurmerk.

🧪 Inhoud

Het potje bevat 1 gram puur YK-11 poeder.
Een maatschep is niet inbegrepen.
Voor nauwkeurige afweging raden we aan om een precisieweegschaal te gebruiken.

📄 Disclaimer

Dit materiaal wordt uitsluitend verkocht voor gebruik in laboratoriumonderzoek. Verkoopvoorwaarden zijn van toepassing. Niet voor menselijke consumptie, noch voor medisch, diergeneeskundig of huishoudelijk gebruik. Maak uzelf vertrouwd met onze DISCLAIMER voordat u bestelt.

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SKU: 51744310902

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4.5 ★★★★★
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A
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Asia
Lowell, US
★★★★★ 5
Absolutely amazing! Must try.
I absolutely love this sponge!, it is so dense; it uses such a small amount of makeup but applies like a full coverage. I am using much less of my mineral makeup powder thanks to this sponge; plus it is easy to wash and dries quickly. Totally worth a try!
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Reviewed in the United States on March 11, 2024
F
Verified Purchase
35 F glitter loving unicorn
Cuba, US
★★★★★ 4
*update* Maybe(?) Perfect for those who hate eggs
Edit: Update It is with a heavy heart Im updating this review. When I said this sponge stains, I mean it really stains. Now to be fair it is marketed as a powder sponge and I use it with liquid so this my be entirely on the user (aka me) but it's like I can never get it clean. Between my repeated washing and the overall product build up the performance of this sponge went downhill quickly. The finish of my makeup suffered and the flocking took a beating. For what it's worth the sponge has not fallen apart and is still in one piece. But I get more of a 4 star finish than a 5 star finish. I've ended up using a large fluffy brush to buff out my foundation to get the desired result. I also ended up repurchasing the flocked flat ended egg from RT to replace this although at the moment I am still stubbornly using this sponge (and also avoiding doing my makeup) I do believe a lot of my issues are do to using this sponge with liquid foundation instead of power and that is on me. I'm finding it so very difficult to clean and the RT flocked egg cleans up so much easier. I don't hate this sponge but my lovefest has definitely taken a turn to more of a likefest. I am going to keep using (because I am stubborn like that) and see how long it takes to turn this relationship into a hatefest or fall apart completely, whichever happens first. I will most likely update again at that time. At this moment I am changing my review from 5 star to 4 star. I will be keeping my original review below. *original review* Yo I LOVE this thing. Ok here's the deal, I don't like the beauty blender, in fact I kinda hate it. Yea, I said it, I'm not on board with bouncing an egg all over my face, I think it's tedious and inefficient. I had at one time a flat teardrop shaped sponge that was my hands down favorite application tool for foundation. I used that thing until it literally fell apart. I tried to find a replacement but the store I had originally gotten it from no longer carried it so I kept using that ratty old sponge until it was missing chunks. I tried some other flat sponges but none worked as I wanted so I went back to brushes but I really hate cleaning foundation from brushes so I was pretty much hating my life. Then I found a flocked egg. Now I'm not a fan of the eggs but I was intrigued by the flocked texture and it had a nice flat edge so I tried it and it was almost as good as my old dearly missed flat teardrop sponge. I still was not a fan of bouncing an egg around on my face but I used this until the flocking wore off (about 6 months) Well, I saw this listing for a flat flocked sponge and I pounced on it. I am so incredibly deliriously happy with this little sponge. I love that it's flat and not an egg. I love the flocking. I love how it fits in my hand. I love love the finish I get with my foundation. I love it. Like I need to order a dozen more so I never run out and I'm trying to break my hoarding tendencies but for this tool I want to hoard. So the bad... It does stain easily. I wet my sponge before use and give it a quick clean after use. My old flocked egg would clean right up but this has stained on the first use. I also don't know how long this will hold up so I hope to update at a later time about that. Overall I couldn't be happier with this sponge.
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Reviewed in the United States on February 10, 2021
K
Verified Purchase
Kristyne
Lexington, US
★★★★★ 5
Perfect for liquid
This sponge is not made for liquid but I use it for my liquid foundation. The sponge won't last as long when it gets wet but it still lasts a LONG time! I put a drop of water on sponge first then dab a few times on my arm to dry with only a slight hint of moisture left (very dry feeling)... then add a drop of makeup (literally). The coverage is awesome and your makeup last 2 to 3x as long. Flawless finish. Love it! I recently updated my review...I still have same awesome sponge. Now I also mix a silicone air brush liquid (clear) to the liquid makeup it spreads farther and the finish is wonderful. Great product stays dry and drys very quick after use.
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Reviewed in the United States on January 19, 2014
D
Verified Purchase
Doris
Los Angeles, US
★★★★★ 5
Love this product!
I’ve used this product for a long time. It’s nice and soft and works well on my skin. I wouldn’t use anything else.
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Reviewed in the United States on July 29, 2024
K
Verified Purchase
kjm27434
Massapequa, US
★★★★★ 3
Its OK, but not nearly as easy to use as videos and reviews make it seem.
I ordered this flocked sponge based on reviews and on watching JI videos of applying pure pressed powder with it. I tried it 'damp' and it was awful mess! I tried it dry, and no powder was transferring to my face at all. I'll stick with my ELF blurring brush to apply JI pressed foundation (which I love).
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Reviewed in the United States on October 12, 2018

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